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1

Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Dataset

Chris Bauer, Frank Kleinjung, Celia J Smith, Mark W Towers, Ali Tiss, Alexandra Chadt, Tanja Dreja, Dieter Beule, Hadi Al-Hasani, Knut Reinert, Johannes Schuchhardt, Rainer Cramer

Journal:

BMC Bioinformatics

Year:

2011

Language:

english

File:

PDF, 1.95 MB

english, 2011

2

High-performance compact SPR sensor for multi-analyte sensing

Milan Vala, Karel Chadt, Marek Piliarik, Jiří Homola

Journal:

Sensors and Actuators B: Chemical

Year:

2010

Language:

english

File:

PDF, 342 KB

english, 2010

3

The Identification of a Chlorinated MDMA

Maresova, V., Hampl, J., Chundela, Z., Zrcek, F., Polasek, M., Chadt, J.

Journal:

Journal of Analytical Toxicology

Year:

2005

Language:

english

File:

PDF, 1.04 MB

english, 2005

4

Project Manager And His/Her Competencies

Cech, Petr, Chadt, Karel

Journal:

International conference KNOWLEDGE-BASED ORGANIZATION

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

5

Identification of Consumer Behavior Based on Price Elasticity: A Case Study of the Prague Market of Accommodation Services

Petricek, Martin, Chalupa, Stepan, Chadt, Karel

Journal:

Year:

2020

File:

PDF, 745 KB

2020

6

Monitoring of dimethyl sulphate-induced N3-methyladenine, N7-methylguanine and O6-methylguanine DNA adducts using reversed-phase high performance liquid chromatography and mass spectrometry

Jiri Chadt, David Sykora, Robert Nilsson, Pavel Vodicka

Journal:

Journal of Chromatography B

Year:

2008

Language:

english

File:

PDF, 373 KB

english, 2008

7

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

Chadt, Alexandra, Leicht, Katja, Deshmukh, Atul, Jiang, Lake Q, Scherneck, Stephan, Bernhardt, Ulrike, Dreja, Tanja, Vogel, Heike, Schmolz, Katja, Kluge, Reinhart

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008

8

Nutrition-/diet-induced changes in gene expression in pancreatic β-cells

A. Chadt, G. S. H. Yeo, H. Al-Hasani

Journal:

Diabetes, Obesity and Metabolism

Year:

2012

Language:

english

File:

PDF, 680 KB

english, 2012

9

Portable Surface Plasmon Resonance Biosensor for Detection of Nucleic Acids

H. Šípová, M. Piliarik, M. Vala, K. Chadt, P. Adam, M. Bocková, K. Hegnerová, J. Homola

Journal:

Procedia Engineering

Year:

2011

Language:

english

File:

PDF, 521 KB

english, 2011

10

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

Chris Bauer, Frank Kleinjung, Dorothea Rutishauser, Christian Panse, Alexandra Chadt, Tanja Dreja, Hadi Al-Hasani, Knut Reinert, Ralph Schlapbach, Johannes Schuchhardt

Journal:

BMC Bioinformatics

Year:

2012

Language:

english

File:

PDF, 324 KB

english, 2012

11

SPIE Proceedings [SPIE SPIE Optics + Optoelectronics - Prague, Czech Republic (Monday 15 April 2013)] Optical Sensors 2013 - Electrochemical surface plasmon resonance biosensor for study of DNA desorption and hybridization

Ferrari, Luca, Šípová, Hana, Tichý, Ivo, Chadt, Karel, Homola, Jiri, Baldini, Francesco, Homola, Jiri, Lieberman, Robert A.

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

12

Tuning in to the rhythm of clock genes in skeletal muscle

Zhou, Zhou, Chadt, Alexandra, Al-Hasani, Hadi

Journal:

Molecular Metabolism

Year:

2014

Language:

english

File:

PDF, 113 KB

english, 2014

13

Deletion of Both Rab-GTPase–Activating Proteins TBC1D1 and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport

Chadt, Alexandra, Immisch, Anja, de Wendt, Christian, Springer, Christian, Zhou, Zhou, Stermann, Torben, Holman, Geoffrey D., Loffing-Cueni, Dominique, Loffing, Johannes, Joost, Hans-Georg, Al-Hasani,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

14

Critical Illness Myopathy and GLUT4

Weber-Carstens, Steffen, Schneider, Joanna, Wollersheim, Tobias, Assmann, Anke, Bierbrauer, Jeffrey, Marg, Andreas, Al Hasani, Hadi, Chadt, Alexandra, Wenzel, Katrin, Koch, Susanne, Fielitz, Jens, Kle

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

15

Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system

Keipert, S., Ost, M., Chadt, A., Voigt, A., Ayala, V., Portero-Otin, M., Pamplona, R., Al-Hasani, H., Klaus, S.

Journal:

AJP Endocrinology and Metabolism

Year:

2013

Language:

english

File:

PDF, 821 KB

english, 2013

16

The ARF-Like GTPase ARFRP1 Is Essential for Lipid Droplet Growth and Is Involved in the Regulation of Lipolysis

Hommel, A., Hesse, D., Volker, W., Jaschke, A., Moser, M., Engel, T., Bluher, M., Zahn, C., Chadt, A., Ruschke, K., Vogel, H., Kluge, R., Robenek, H., Joost, H.-G., Schurmann, A.

Journal:

Molecular and Cellular Biology

Year:

2010

Language:

english

File:

PDF, 4.41 MB

english, 2010

17

Re-patterning of Skeletal Muscle Energy Metabolism by Fat Storage-inducing Transmembrane Protein 2

Miranda, D. A., Koves, T. R., Gross, D. A., Chadt, A., Al-Hasani, H., Cline, G. W., Schwartz, G. J., Muoio, D. M., Silver, D. L.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 2.62 MB

english, 2011

18

Deletion of Both Rab-GTPase–Activating Proteins TBC14KO and TBC1D4 in Mice Eliminates Insulin- and AICAR-Stimulated Glucose Transport. Diabetes 2015;64:746–759

Chadt, Alexandra, Immisch, Anja, de Wendt, Christian, Springer, Christian, Zhou, Zhou, Stermann, Torben, Holman, Geoffrey D., Loffing-Cueni, Dominique, Loffing, Johannes, Joost, Hans-Georg, Al-Hasani,

Journal:

Year:

2015

File:

PDF, 550 KB

2015

19

Surface plasmon resonance optical cavity enhanced refractive index sensing

Giorgini, A., Avino, S., Malara, P., Gagliardi, G., Casalino, M., Coppola, G., Iodice, M., Adam, P., Chadt, K., Homola, J., De Natale, P.

Journal:

Year:

2013

Language:

english

File:

PDF, 516 KB

english, 2013

20

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, A. S., Chibalin, A. V., Bjornholm, M., Al-Hasani, H., Zierath, J. R.

Journal:

AJP Endocrinology and Metabolism

Year:

2012

Language:

english

File:

PDF, 620 KB

english, 2012

21

Chloramphenicol and acute esophagitis in the emergency department

Andicochea, ChadT, Portouw, StevenJ, Bokan, MelissaM

Journal:

Journal of Emergencies Trauma and Shock

Year:

2015

Language:

english

File:

PDF, 397 KB

english, 2015

22

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

Lizunov, V. A., Stenkula, K. G., Lisinski, I., Gavrilova, O., Yver, D. R., Chadt, A., Al-Hasani, H., Zimmerberg, J., Cushman, S. W.

Journal:

AJP Endocrinology and Metabolism

Year:

2012

Language:

english

File:

PDF, 2.93 MB

english, 2012

23

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle

Wiza, Claudia, Chadt, Alexandra, Blumensatt, Marcel, Kanzleiter, Timo, Herzfeld De Wiza, Daniella, Horrighs, Angelika, Mueller, Heidi, Nascimento, Emmani B.M., Schürmann, Annette, Al-Hasani, Hadi, Ouw

Journal:

Archives of Physiology and Biochemistry

Year:

2014

Language:

english

File:

PDF, 976 KB

english, 2014

24

Conventional Knockout of Tbc1d1 in Mice Impairs Insulin- and AICAR-Stimulated Glucose Uptake in Skeletal Muscle

Dokas, Janine, Chadt, Alexandra, Nolden, Tobias, Himmelbauer, Heinz, Zierath, Juleen R., Joost, Hans-Georg, Al-Hasani, Hadi

Journal:

Year:

2013

Language:

english

File:

PDF, 2.21 MB

english, 2013

25

Toward single-molecule detection with sensors based on propagating surface plasmons

Kvasnička, Pavel, Chadt, Karel, Vala, Milan, Bocková, Markéta, Homola, Jiří

Journal:

Year:

2012

Language:

english

File:

PDF, 320 KB

english, 2012

26

Whole-exome sequencing identifies mutations ofTBC1D1encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT)

Kosfeld, Anne, Kreuzer, Martin, Daniel, Christoph, Brand, Frank, Schäfer, Anne-Kathrin, Chadt, Alexandra, Weiss, Anna-Carina, Riehmer, Vera, Jeanpierre, Cécile, Klintschar, Michael, Bräsen, Jan Hinric

Journal:

Year:

2016

Language:

english

File:

PDF, 12.46 MB

english, 2016

27

Tbc1d1 deletion suppresses obesity in leptin-deficient mice

Dokas, J, Chadt, A, Joost, H-G, Al-Hasani, H

Journal:

International Journal of Obesity

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

28

SPIE Proceedings [SPIE SPIE BiOS: Biomedical Optics - San Jose, CA (Saturday 24 January 2009)] Plasmonics in Biology and Medicine VI - Compact multi-channel high-sensitivity biosensor based on spectroscopy of surface plasmons

Piliarik, Marek, Vo-Dinh, Tuan, Lakowicz, Joseph R., Hegnerová, Kateřiná, Vala, Milan, Chadt, Karel, Tichý, Ivo, Homola, Jiří

Year:

2009

Language:

english

File:

PDF, 489 KB

english, 2009

29

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

Zhou, Zhou, Menzel, Franziska, Benninghoff, Tim, Chadt, Alexandra, Du, Chen, Holman, Geoffrey D., Al-Hasani, Hadi

Journal:

Year:

2017

Language:

english

File:

PDF, 370 KB

english, 2017

30

Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway

Görgens, Sven W., Benninghoff, Tim, Eckardt, Kristin, Springer, Christian, Chadt, Alexandra, Melior, Anita, Wefers, Jakob, Cramer, Andrea, Jensen, Jørgen, Birkeland, Kåre I., Drevon, Christian A., Al-

Journal:

Year:

2017

Language:

english

File:

PDF, 876 KB

english, 2017

31

Absence of the kinase S6k1 mimics the effect of chronic endurance exercise on glucose tolerance and muscle oxidative stress

Binsch, C., Jelenik, T., Pfitzer, A., Dille, M., Müller-Lühlhoff, S., Hartwig, S., Karpinski, S., Lehr, S., Kabra, D., Chadt, A., Roden, M., Al-Hasani, H., Castañeda, T.R.

Journal:

Molecular Metabolism

Year:

2017

Language:

english

File:

PDF, 1.79 MB

english, 2017

32

Regulation of RabGAPs involved in insulin action

Mafakheri, Samaneh, Chadt, Alexandra, Al-Hasani, Hadi

Journal:

Biochemical Society Transactions

Year:

2018

Language:

english

File:

PDF, 2.28 MB

english, 2018

33

An Interval of the Obesity QTL Nob3.38 within a QTL Hotspot on Chromosome 1 Modulates Behavioral Phenotypes

Vogel, Heike, Montag, Dirk, Kanzleiter, Timo, Jonas, Wenke, Matzke, Daniela, Scherneck, Stephan, Chadt, Alexandra, Töle, Jonas, Kluge, Reinhart, Joost, Hans-Georg, Schürmann, Annette, Palmer, Abraham

Journal:

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

34

FGF21 regulates insulin sensitivity following long-term chronic stress

Jelenik, Tomas, Dille, Matthias, Müller-Lühlhoff, Sabrina, Kabra, Dhiraj G., Zhou, Zhou, Binsch, Christian, Hartwig, Sonja, Lehr, Stefan, Chadt, Alexandra, Peters, Eva M.J., Kruse, Johannes, Roden, Mi

Journal:

Molecular Metabolism

Year:

2018

Language:

english

File:

PDF, 3.37 MB

english, 2018

35

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Thomas, Elaine C, Hook, Sharon C, Gray, Alexander, Chadt, Alexandra, Carling, David, Al-Hasani, Hadi, Heesom, Kate J, Hardie, D. Grahame, Tavaré, Jeremy M.

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 10.40 MB

english, 2018

36

AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

Mafakheri, Samaneh, Flörke, Ralf R., Kanngießer, Sibylle, Hartwig, Sonja, Espelage, Lena, De Wendt, Christian, Schönberger, Tina, Hamker, Nele, Lehr, Stefan, Chadt, Alexandra, Al-Hasani, Hadi

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 13.37 MB

english, 2018

37

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

Kjøbsted, Rasmus, Roll, Julie L.W., Jørgensen, Nicolas O., Birk, Jesper B., Foretz, Marc, Viollet, Benoit, Chadt, Alexandra, Al-Hasani, Hadi, Wojtaszewski, Jørgen F.P.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.44 MB

english, 2019

38

P3476High-resolution respirometry reveals enhanced myocardial mitochondrial ketone oxidation after fasting and ventricular unloading

Zweck, E, Burkart, V, Wessel, C, Scheiber, D, Leung, K H M, Chadt, A, Pesta, D, Boeken, U, Akhyari, P, Roden, M, Kelm, M, Szendroedi, J, Westenfeld, R

Journal:

European Heart Journal

Year:

2019

Language:

english

File:

PDF, 91 KB

english, 2019

39

P3476High-resolution respirometry reveals enhanced myocardial mitochondrial ketone oxidation after fasting and ventricular unloading

Zweck, E, Burkart, V, Wessel, C, Scheiber, D, Leung, K H M, Chadt, A, Pesta, D, Boeken, U, Akhyari, P, Roden, M, Kelm, M, Szendroedi, J, Westenfeld, R

Journal:

European Heart Journal

Year:

2019

File:

PDF, 91 KB

2019

40

Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

Chadt, Alexandra, Al-Hasani, Hadi

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2020

File:

PDF, 2.73 MB

2020

41

Identification of Novel Potential Type 2 Diabetes Genes Mediating Î²-Cell Loss and Hyperglycemia Using Positional Cloning

Aga, Heja, Hallahan, Nicole, Gottmann, Pascal, Jaehnert, Markus, Osburg, Sophie, Schulze, Gunnar, Kamitz, Anne, Arends, Danny, Brockmann, Gudrun, Schallschmidt, Tanja, Lebek, Sandra, Chadt, Alexandra,

Journal:

Frontiers in Genetics

Year:

2020

File:

PDF, 7.73 MB

2020

42

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

Hook, Sharon C., Chadt, Alexandra, Heesom, Kate J., Kishida, Shosei, Al-Hasani, Hadi, TavarÃ©, Jeremy M., Thomas, Elaine C.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 2.86 MB

2020